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The Mystery of Life and DNA

A four-letter code that builds every living thing

Your genome

3 billionletters in one copy of the human genome
4chemical letters: A, T, C and G
~20,000genes that code for proteins
6 feetof DNA in a single cell, if stretched out

Most cells carry two copies, one from each parent.

From code to living thing

  1. DNA stores the recipeGenes are stretches of the four-letter code
  2. RNA copies a geneA working copy carries the message out
  3. Ribosomes read itThree letters at a time choose amino acids
  4. Proteins do the workBuilding tissue, digesting food, fighting germs

1953

Watson and Crick described the double helix, building on Rosalind Franklin's X-ray images.

What we know and don't

Known

  • How DNA copies itself
  • How genes become proteins
  • The full human sequence, finished in 2003

Still unknown

  • How the first living cells formed
  • How the first self-copying molecules arose
  • Whether life began elsewhere too

Sources: National Human Genome Research Institute; Nature

Remember

Four chemical letters, arranged in 3 billion steps, spell out a human being, but how life first began is still unsolved.